Highlights
- Continuing antidepressant medications during pregnancy is associated with a reduced risk of postpartum depression compared to stopping or intermittent use.
- Severity of depressive symptoms at pregnancy onset strongly predicts postpartum depression risk, emphasizing the importance of early screening.
- Risk reduction benefits of antidepressant continuation do not significantly differ across racial, ethnic, or age groups, supporting broad clinical applicability.
- Shared decision-making informed by prenatal depressive symptom severity is crucial to optimize maternal mental health outcomes.
Background
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For clinical reference; use professional judgment.
