Uncertain Evidence for Youth Suicide Interventions: DBT Shows Promise While Medications and Neurotherapies Remain Largely Unstudied

Highlight

– A comprehensive 2025 systematic review of 65 studies (14,534 youths) found only moderate-strength evidence that dialectical behavior therapy (DBT) reduces suicidal ideation in adolescents; other psychosocial treatments provide low or insufficient evidence for suicidal outcomes.

– Acute brief interventions, school- and community-based programs, and pharmacologic, neurotherapeutic, and emerging therapies remain inadequately studied in youths at heightened suicide risk.

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