Posted inAnesthesiology Neurology news
Lacosamide Lowers Peripheral Nerve Excitability in Large Myelinated Fibers: Randomized Crossover Evidence and Biomarker Implications
A randomized, double‑blind crossover trial in healthy volunteers found lacosamide acutely reduced strength–duration time constant and other excitability metrics in large myelinated peripheral fibers; pregabalin and tapentadol produced no comparable changes.