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SCORE2

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Synergistic Integration of Metabolomics and Polygenic Scores Doubles the Impact of Cardiovascular Risk Prediction Models
Posted inCardiology news Public Health

Synergistic Integration of Metabolomics and Polygenic Scores Doubles the Impact of Cardiovascular Risk Prediction Models

Posted by MedXY By MedXY 01/05/2026
A large-scale UK Biobank study demonstrates that combining NMR metabolomics and polygenic risk scores with the SCORE2 framework significantly improves cardiovascular risk discrimination, potentially doubling the number of preventable events in population-wide screening programs.
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