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NPM1

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Decoding Clonal Evolution and Immunophenotype in NPM1-Mutated AML through Single-Cell Multiomics
Posted inHematology-Oncology news

Decoding Clonal Evolution and Immunophenotype in NPM1-Mutated AML through Single-Cell Multiomics

Posted by By MedXY 07/02/2026
Single-cell multiomic analysis reveals how genotype-immunophenotype relationships shape clonal evolution in NPM1-mutated acute myeloid leukemia, highlighting implications for prognosis and therapy response.
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Triplet Therapy Advances: Azacitidine, Venetoclax, and Revumenib in Newly Diagnosed NPM1-Mutated or KMT2A-Rearranged AML
Posted inClinical Updates Hematology-Oncology news Specialties

Triplet Therapy Advances: Azacitidine, Venetoclax, and Revumenib in Newly Diagnosed NPM1-Mutated or KMT2A-Rearranged AML

Posted by By MedXY 08/07/2025
A phase I trial demonstrates high remission rates and manageable safety for azacitidine, venetoclax, and revumenib in older adults with newly diagnosed NPM1-mutated or KMT2A-rearranged AML, offering new hope for these high-risk patients.
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  • Frailty as a Predictor of Surgical Outcomes in Cricopharyngeus Muscle Dysfunction: Enhancing Patient Selection and Expectations
  • Histopathologic Insights in Chronic Rhinosinusitis Linked to Intranasal Substance Use: Implications for Clinical Management
  • Environmental Burden and Its Influence on Surgical Outcomes: Unveiling the Hidden Disparities
  • Advancing Surgical Quality Assessment in Distal Gastrectomy: Automated Evaluation of the Critical View of Quality Using Computer Vision
  • Neurotensin Receptor 1: A Key Driver of Immune Exclusion and Poor Prognosis in Colorectal Cancer
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