Posted inCardiology news
Oxidized Phospholipid PGPC Impedes Angiogenesis by Disrupting Endothelial Autophagy via NPC1-Mediated Syntaxin 17 Modification
The oxidized phospholipid PGPC inhibits angiogenesis in ischemic heart disease by impairing endothelial autophagic flux through NPC1-induced acetylation and ubiquitination of syntaxin 17, unveiling new potential therapeutic targets for coronary artery disease.