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Neonatal Immunity

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Maternal Nipocalimab Therapy for Severe HDFN: Evidence of Neonatal Safety and Immunological Recovery
Posted innews Pediatrics

Maternal Nipocalimab Therapy for Severe HDFN: Evidence of Neonatal Safety and Immunological Recovery

Posted by By MedXY 01/31/2026
The UNITY study demonstrates that antenatal nipocalimab treatment for severe HDFN effectively reduces fetal risk while resulting in only transient neonatal hypogammaglobulinemia. Findings confirm low fetal drug exposure and robust long-term immune recovery, including normal vaccine responses by 96 weeks.
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