metastasis – Medxy AI

Genomic Profiling of Primary Gastric Tumors Predicts Recurrence Patterns and Survival Outcomes

By MedXY 08/09/2026

Genomic alterations in primary gastric tumors, including KRAS and PIK3CA mutations, correlate with recurrence risk and metastatic patterns, informing personalized postoperative surveillance and treatment strategies.

news Oncology

Genomic Evolution of Breast Cancer: How Acquired Gene Fusions Drive Metastatic Progression and Treatment Resistance

By MedXY 01/11/2026

A multi-omics analysis from the AURORA program reveals that metastatic breast cancer carries a significantly higher burden of gene fusions than primary tumors. Acquired fusions, particularly involving ESR1, are linked to genomic instability and poor clinical outcomes.

Clinical Updates Oncology

Novel Heparanase Inhibitor LMW-DSS Shows Promise in Preventing Breast Cancer Metastasis by Targeting Migration and Angiogenesis

By MedXY 09/30/2025

Low-molecular-weight dextran sulfate sodium (LMW-DSS), a new heparanase inhibitor, effectively prevents breast cancer metastasis in mice by inhibiting cancer cell migration and angiogenesis, offering a promising therapeutic approach with minimal bleeding risk.

Clinical Updates Family Medicine & Nutrition news Oncology Specialties

The Dark Side of Olive Oil: High-Oil Diets Promote Lung Metastasis in Triple-Negative Breast Cancer

By MedXY 09/16/2025

Recent research reveals that high-fat diets rich in olive oil, while not impairing immunity, significantly promote lung metastasis of triple-negative breast cancer via a novel fatty acid-driven mechanism involving FABP5 and ALDH pathways.