Posted inInfectious Diseases Neurology news
Adjunct Dexamethasone in Herpes Simplex Encephalitis: Safe but Fails to Improve Long-Term Verbal Memory in the DexEnceph Trial
The Phase 3 DexEnceph trial found that adjunct dexamethasone is safe in adults with HSV encephalitis but does not significantly improve verbal memory scores at 26 weeks compared to aciclovir monotherapy, suggesting a need for earlier or more targeted immunomodulation.