first-line treatment

Evolving First-Line Treatments in Primary Mediastinal B-Cell Lymphoma: Insights from a Nationwide Italian Retrospective Study

By MedXY 09/30/2026

This retrospective nationwide study from Italy evaluates real-life first-line treatments for primary mediastinal B-cell lymphoma, highlighting treatment patterns, clinical outcomes, and challenges in managing this rare lymphoma subtype.

Hematology-Oncology news Oncology

First-Line Serplulimab in Extensive-Stage Small Cell Lung Cancer: Secondary Analysis of the ASTRUM-005 Phase 3 Randomized Clinical Trial

By MedXY 06/07/2026

Extended follow-up from ASTRUM-005 shows serplulimab plus chemotherapy improves long-term survival in untreated extensive-stage small cell lung cancer, with manageable safety and encouraging patient-reported outcomes.

news Oncology Respiratory Specialties

Comparative Efficacy and Safety of Prednisone and Methotrexate as First-Line Treatments for Pulmonary Sarcoidosis

By MedXY 08/01/2025

A recent multicenter trial demonstrates methotrexate's noninferiority to prednisone in improving lung function at 24 weeks in pulmonary sarcoidosis, with distinct side-effect profiles informing treatment choices.