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disease severity

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Unveiling Non-Genetic Influences on Hereditary Ataxia: Insights from SCA6 and SCA27B Cohorts
Posted inNeurology news

Unveiling Non-Genetic Influences on Hereditary Ataxia: Insights from SCA6 and SCA27B Cohorts

Posted by By MedXY 08/26/2026
This study identifies key nongenetic factors impacting disease onset and severity in hereditary ataxias SCA6 and SCA27B, highlighting environmental exposures and demographics as important modifiers beyond genetic mutations.
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Genetic Risk of Inflammatory Bowel Disease Linked to Disease Severity
Posted inGastroenterology news

Genetic Risk of Inflammatory Bowel Disease Linked to Disease Severity

Posted by By MedXY 05/01/2026
A Danish nationwide study reveals higher genetic risk scores for IBD predict more severe disease courses, including increased surgery rates, stronger medication needs, and worse inflammatory markers in both Crohn's and ulcerative colitis patients.
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  • Germline MSH3 and MLH3 Mutations as Tumor Suppressors Elevating Colorectal Cancer Risk via Hypermutation Signature ID4
  • Natural History and Treatment Outcomes in Hemorrhagic Moyamoya Disease: Insights from a Large Chinese Cohort
  • Unraveling Bibrachial Amyotrophy in Spontaneous Spinal CSF Leaks: Clinical Insights and Surgical Outcomes
  • Circulating Metabolites as Emerging Biomarkers for Stroke Risk Prediction: Insights from the BiomarCaRE Project
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