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One High‑Fat Meal, Four Hours: Rapid Impairment of Vascular Function and Brain Blood‑Flow Regulation
A controlled study from the University of New South Wales shows a single high‑fat meal (130 g fat) produces marked postprandial hypertriglyceridaemia and measurable declines in systemic endothelial function and dynamic cerebral autoregulation within 4 hours, effects magnified in older men.