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Vutrisiran Treatment and Cardiovascular MRI-Detected Changes in Cardiac Structure, Function, and Amyloid Burden in ATTR-CM
Vutrisiran, an RNA interference therapeutic, significantly improves cardiac function, reduces amyloid burden, and attenuates disease progression in transthyretin amyloid cardiomyopathy as revealed by multiparametric cardiovascular MRI and corroborated by echocardiographic findings.