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cardiac inflammation

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Metabolic Splicing Nexus: HNRNPK Lactylation Drives Inflammation and Injury in Myocardial Ischemia/Reperfusion
Posted inCardiology news

Metabolic Splicing Nexus: HNRNPK Lactylation Drives Inflammation and Injury in Myocardial Ischemia/Reperfusion

Posted by By MedXY 09/14/2026
Lactylation of HNRNPK at K405 links metabolic stress to inflammatory RNA splicing, promoting pathological Jag2 isoform expression and exacerbating myocardial ischemia/reperfusion injury, revealing novel therapeutic targets.
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