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Personalised T-Cell Activation Shows Promise in Overcoming Minimal Residual Disease in Chronic Lymphocytic Leukaemia
Posted inHematology-Oncology news

Personalised T-Cell Activation Shows Promise in Overcoming Minimal Residual Disease in Chronic Lymphocytic Leukaemia

Posted by MedXY By MedXY 02/18/2026
A Phase 1 study demonstrates that iTAC-XS15-CLL01, a personalised multipeptide T-cell activator, induces robust immune responses in 95% of CLL patients on BTK inhibitors, offering a potential path to sustainable cancer control and eradication of minimal residual disease.
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Fenebrutinib Achieves 69% Reduction in New Brain Lesions for Relapsing Multiple Sclerosis: Insights from the FENopta Phase 2 Trial
Posted inNeurology news Rheumatology

Fenebrutinib Achieves 69% Reduction in New Brain Lesions for Relapsing Multiple Sclerosis: Insights from the FENopta Phase 2 Trial

Posted by MedXY By MedXY 12/23/2025
The Phase 2 FENopta trial demonstrates that fenebrutinib, a highly selective, reversible BTK inhibitor, significantly reduces MRI disease activity by 69% in relapsing multiple sclerosis while maintaining a favorable safety profile over 48 weeks.
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  • Large Multi-Center EMR Cohort Suggests NSAID Exposure Is Associated With Lower Future Risk of Age-Related Macular Degeneration
  • Sustained Locoregional Control With Deintensified Chemoradiotherapy for HPV Oropharyngeal Carcinoma
  • Impact of Immunocompromise on Survival in HPV-Positive Throat Cancer Patients
  • Adherence to Surveillance in the Watch and Wait Approach for Rectal Cancer
  • Rectal Cancer Accreditation Was Linked to Higher Hospital Volume Without More Care Fragmentation
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