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Polygenic Influences and Anticholinergic Burden: Unraveling Their Joint Impact on Cognition and Brain Structure in Psychosis Spectrum Disorders
Posted inNeurology news Psychiatry

Polygenic Influences and Anticholinergic Burden: Unraveling Their Joint Impact on Cognition and Brain Structure in Psychosis Spectrum Disorders

Posted by MedXY By MedXY 10/30/2025
This study reveals that genetic predispositions interact with anticholinergic medication burden to influence cognitive deficits and brain gray matter volume reductions in psychosis spectrum disorders, offering new insights into personalized treatment strategies.
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Life Course Air Pollution Exposure and Cognitive Decline: Insights from the 1946 British Birth Cohort
Posted inNeurology news Public Health

Life Course Air Pollution Exposure and Cognitive Decline: Insights from the 1946 British Birth Cohort

Posted by MedXY By MedXY 10/20/2025
This population-based study reveals that midlife exposure to nitrogen dioxide and particulate matter correlates with poorer cognitive function and adverse brain structural changes in later life, underscoring the neurocognitive risks of air pollution.
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  • Reduced-Intensity Thiotepa Plus Post-Transplant Cyclophosphamide Delivers Near-Universal Engraftment and Minimal GVHD in Matched Sibling Transplantation for Adolescents and Adults With Sickle Cell Disease
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