Higher Amyloid PET Signal and Lower APOE ε4 Frequency Distinguish Iatrogenic From Sporadic Cerebral Amyloid Angiopathy
A single-center cross-sectional study found that iatrogenic cerebral amyloid angiopathy carries a higher amyloid PET burden, weaker CSF-PET coupling, and less APOE ε4 enrichment than sporadic disease, supporting a biologically distinct mechanism.
