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amyloid

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Posted inNeurology news Public Health

Brain Imaging Biomarkers and Cognitive Outcomes in a Multidomain Lifestyle Intervention: The POINTER Imaging Ancillary Study

Posted by By MedXY 06/17/2026
The POINTER Imaging study found no overall brain biomarker changes from a structured lifestyle intervention, but participants with lower baseline hippocampal volume showed greater cognitive benefit, suggesting imaging may help identify who responds best.
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Tau Links Amyloid and Vascular Burden to Faster Clinical Decline: Chronicity Reveals Synergy Between White Matter Injury and Amyloid in Dementia Progression
Posted inNeurology news

Tau Links Amyloid and Vascular Burden to Faster Clinical Decline: Chronicity Reveals Synergy Between White Matter Injury and Amyloid in Dementia Progression

Posted by By MedXY 11/05/2025
Longer years above amyloid and white matter hyperintensity positivity predict faster clinical decline. White matter vascular burden amplifies amyloid-related progression, and tau accumulation mediates this effect, highlighting targets and timing for intervention.
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