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ADAMTS13

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Recombinant ADAMTS13 Therapy Demonstrates Superior Efficacy and Safety Over Plasma-Based Therapy in Congenital Thrombotic Thrombocytopenic Purpura: Final Phase 3 Trial Results
Posted inHematology-Oncology news

Recombinant ADAMTS13 Therapy Demonstrates Superior Efficacy and Safety Over Plasma-Based Therapy in Congenital Thrombotic Thrombocytopenic Purpura: Final Phase 3 Trial Results

Posted by By MedXY 09/28/2026
Final phase 3 trial analysis confirms recombinant ADAMTS13 (rADAMTS13) provides effective prophylaxis with fewer acute and subacute TTP events and better safety than plasma-based therapy in congenital TTP patients.
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Long-term Outcomes in Congenital TTP: Registry Data Show Prophylactic Plasma Reduces Clinical Events but Symptoms and Product Burden Persist
Posted inHematology-Oncology news

Long-term Outcomes in Congenital TTP: Registry Data Show Prophylactic Plasma Reduces Clinical Events but Symptoms and Product Burden Persist

Posted by By MedXY 11/15/2025
UK registry follow-up of 104 congenital TTP patients shows regular plasma prophylaxis lowers acute episodes and end‑organ events, but residual symptoms and plasma-related issues drive many patients to recombinant ADAMTS13.
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