Specialties – Page 116

Elevated Serotonin Release in Schizophrenia: New Insights Into Negative Symptom Pathophysiology

By MedXY 12/17/2025

A PET imaging study reveals increased frontal serotonin release in schizophrenia, particularly in deficit type, tied to worse negative symptoms.

Cardiology Neurology news

Combined Cardiorespiratory and Resistance Training After Stroke: Small Gains, Big Questions

By MedXY 12/17/2025

Evidence suggests combined aerobic and strength training post-stroke yields modest improvements in fitness and function but uncertain long-term benefits.

Neurology news

Do Behavioural, Self-Management, and Service Delivery Models Improve Outcomes in Adults with Epilepsy?

By MedXY 12/17/2025

A Cochrane review finds limited and low- to moderate-certainty evidence that behavioural, self-management, or service delivery interventions improve seizure control or quality of life in adults with epilepsy.

Diabetes & Endocrinology Neurology news

Omega-3 Fatty Acids Show Limited Benefits for Diabetic Peripheral Neuropathy

By MedXY 12/17/2025

Current evidence suggests minimal impact of omega-3 supplementation on neuropathy symptoms or quality of life in adults with diabetes.

Cardiology news

Rare but High-Risk: New-Onset RBBB After TAVR Strongly Linked to Pacemaker Need

By MedXY 12/17/2025

New-onset right bundle branch block after TAVR is rare but carries a high risk of requiring permanent pacing within one week.

Cardiology news

Prophylactic Pacemakers After TAVR: Low Pacing Burden Raises Questions on Routine Use

By MedXY 12/17/2025

One-fourth of TAVR patients receive prophylactic pacemakers, but most have minimal pacing needs at 30 days.

Cardiology news

PROMOTE Study Validates Algorithm for Conduction Disturbance Management After TAVR

By MedXY 12/17/2025

A prospective multicenter study confirms that a prespecified algorithm for conduction disturbance management after TAVR is safe, with low sudden cardiac death risk but persistent high pacemaker rates.

Cardiology news

Distinct Mechanisms Drive Early and Delayed Heart Block After TAVR: Insights from Boston Cohort Study

By MedXY 12/17/2025

Prospective cohort study reveals AV nodal versus infranodal conduction patterns underpinning timing of heart block after TAVR.

news Orthopedics

Cryotherapy After Total Knee Replacement: Limited Evidence for Modest Benefits

By MedXY 12/16/2025

Low-certainty evidence suggests cryotherapy may slightly reduce blood loss, pain, and swelling after total knee replacement, but clinical relevance remains uncertain.

Critical Care news Pediatrics

Rethinking Oxygen Strategies for Preterm Infant Resuscitation: Evidence from TORPIDO, IPD-MA, and DCC Trials

By MedXY 12/16/2025

Recent trials and meta-analyses challenge assumptions about optimal initial oxygen levels for preterm resuscitation.

news Oncology

Broad Genetic Testing Reveals Hidden Breast Cancer Risk in Women Without Family History

By MedXY 12/16/2025

The WISDOM trial found that 3.1% of women without breast cancer carried pathogenic variants in key susceptibility genes, many outside existing testing guidelines.

news OB/GYN & Women's Health

Progestagens Show Moderate Efficacy for Endometriosis Pain, But Evidence Variability Limits Clinical Certainty

By MedXY 12/16/2025

Oral progestagens reduce overall pain and dysmenorrhoea in endometriosis, but comparative benefits over other hormonal therapies remain uncertain.

news OB/GYN & Women's Health Oncology

Simple vs Radical Hysterectomy: Balancing Survival Outcomes and Quality of Life in Early Cervical Cancer

By MedXY 12/16/2025

Evidence suggests simple hysterectomy with pelvic lymphadenectomy may offer similar survival outcomes to radical hysterectomy in early-stage cervical cancer, with fewer adverse events and better short-term quality of life.

news OB/GYN & Women's Health Pediatrics

Immediate and Early Skin-to-Skin Contact After Birth: What the 2025 Cochrane Update Means for Practice

By MedXY 12/16/2025

A clear, evidence-based summary of the 2025 Cochrane review on immediate/early skin-to-skin contact (SSC), its impact on breastfeeding and newborn physiology, gaps in maternal outcomes, and practical recommendations for clinical implementation.

Cardiology Internal Medicine news

Riboflavin and Blood Pressure: Evidence Remains Uncertain Despite Genetic Promise

By MedXY 12/16/2025

Cochrane review shows uncertain effects of riboflavin on blood pressure, highlighting a need for larger and better-quality trials.

Neurology news Pediatrics

Limited Evidence for Behavioural and Service Delivery Interventions in Childhood Epilepsy: Urgent Need for Robust Trials

By MedXY 12/16/2025

Current evidence for behavioural and service delivery interventions in childhood epilepsy is scarce and of low quality, highlighting an urgent need for rigorous, long-term trials.