Neurology – Page 5

Reevaluating Early Blood Pressure Targets in Acute Spinal Cord Injury: Insights from a Multicenter Randomized Trial

By MedXY 09/20/2025

A recent randomized clinical trial comparing augmented to conventional blood pressure targets in acute spinal cord injury found no improvement in 6-month neurological outcomes, challenging current practices and highlighting risks of higher blood pressure management.

Clinical Updates Neurology news

Intravenous Antihypertensives Post-Endovascular Thrombectomy: Implications for Functional Recovery in Acute Ischemic Stroke

By MedXY 09/19/2025

Intravenous antihypertensive use within 24 hours after successful EVT in acute ischemic stroke associates with poorer functional outcomes and higher mortality, underscoring the need for cautious blood pressure management strategies post-thrombectomy.

Clinical Updates Diabetes & Endocrinology Neurology news Specialties

Fulmetibant’s Role in Diabetic Neuropathic Pain: Insights from the Phase 2a BRADiNP Study

By MedXY 09/18/2025

The BRADiNP study found that fulmetibant, a bradykinin-1 receptor antagonist, failed to significantly reduce diabetic neuropathic pain compared to placebo, despite favorable safety profiles, highlighting challenges in translating preclinical success to clinical efficacy.

$Pitolisant as Adjunct Therapy for Refractory Restless Legs Syndrome: Insights from a Pilot Study$

Clinical Updates Neurology news Pediatrics Specialties

Pitolisant as Adjunct Therapy for Refractory Restless Legs Syndrome: Insights from a Pilot Study

By MedXY 09/17/2025

This pilot study reveals that adjunctive pitolisant, a histamine-3 inverse agonist, is well tolerated and improves symptom scales in refractory restless legs syndrome, suggesting potential to address daytime consequences with minimal core symptom relief. Controlled trials are warranted.

Critical Care Neurology Specialties

Lung-Protective Mechanical Ventilation in Acute Brain Injury: Insights from the PROLABI Trial

By MedXY 09/17/2025

The PROLABI trial assessed lung-protective ventilation in acute brain injury patients and found no improvement in mortality, ventilator dependency, or ARDS incidence, highlighting the need for further research in this population.

Neurology news Specialties

Electrical Vestibular Stimulation: A Promising Adjunct Therapy for Adult Insomnia in Hong Kong

By MedXY 09/17/2025

A double-blind, randomized trial demonstrates that electrical vestibular stimulation (VeNS) significantly reduces insomnia severity and improves quality of life in adults, highlighting a novel non-pharmacological treatment option.

Diabetes & Endocrinology Neurology news Specialties

Unlocking Precision Nutrition: Genetic Insights from the MIND Diet Trial for Cognitive Health

By MedXY 09/16/2025

This article explores the genetic data resource from the MIND trial, highlighting its potential to tailor dietary interventions to mitigate cognitive decline and advance precision nutrition for Alzheimer's risk populations.

Clinical Updates Family Medicine & Nutrition Neurology Pediatrics Specialties

Decoding Metabolic Adaptation: Caloric Restriction’s Impact on Organ Size in the CALERIE 2 Trial

By MedXY 09/16/2025

This study explores how caloric restriction influences organ size and metabolic adaptation, using MRI data from the CALERIE 2 trial, revealing nuanced changes in energy expenditure linked to organ-specific tissue loss.

Allergy & Immunology Neurology Pediatrics Specialties

Modulating Immune Dysregulation in Autism Spectrum Disorder: Comparative Effects of an Anti-Inflammatory Diet and Probiotic Supplementation

By MedXY 09/16/2025

A 12-week trial in children with ASD demonstrates that a structured anti-inflammatory dietary protocol (NeuroGutPlus) exerts broader immunoregulatory effects than multi-strain probiotics, highlighting diet as a promising non-pharmacological intervention for immune dysregulation in ASD.

Family Medicine & Nutrition Neurology news Specialties

Unlocking Better Sleep: How Daily Walnut Consumption Enhances Melatonin Metabolism and Sleep Quality in Young Adults

By MedXY 09/16/2025

A randomized crossover trial shows that daily intake of 40 g walnuts increases urinary 6-sulfatoxymelatonin, reduces sleep latency, and improves global sleep quality in young adults, highlighting walnuts' potential as a natural sleep aid.

Neurology news Specialties

Enhanced Gait Rehabilitation in Chronic Stroke: Combining High-Intensity Interval Training with Robot-Assisted Gait Therapy

By MedXY 09/14/2025

A randomized controlled trial demonstrates that combining high-intensity interval training with robot-assisted gait therapy significantly improves gait speed, balance, and lower limb function in patients with chronic stroke compared to treadmill therapy alone.

AI Neurology news Specialties

Evaluating AI-Enhanced EMG Reporting: Insights from a Randomized Controlled Trial

By MedXY 09/14/2025

An RCT evaluated an AI-assisted framework for electrodiagnostic report interpretation, finding no significant improvement over standard physician reporting but highlighting potential workflow benefits for routine cases.

Family Medicine & Nutrition Medical News Neurology news Specialties

How B Vitamins Can Slow Brain Shrinkage and Prevent Dementia？

By MedXY 09/11/2025

Long-term studies reveal that proper supplementation of B vitamins can slow brain atrophy, improve cognitive function, and reduce dementia risk, especially in older adults at risk of deficiency.

Clinical Updates Neurology news Specialties

Small Financial Incentives Boost Enrollment in Memory Study but Do Not Enhance Racial Diversity

By MedXY 09/11/2025

A randomized trial shows that guaranteed small financial rewards increase enrollment in an Alzheimer’s prevention registry among economically diverse older adults, whereas lottery prizes do not, with limited impact on racial and ethnic representation.

Clinical Updates Neurology Specialties

Optimizing Head Positioning in Large Vessel Occlusion Stroke Before Thrombectomy: Evidence from a Randomized Clinical Trial

By MedXY 09/11/2025

A recent randomized clinical trial demonstrates that 0° head-of-bed positioning prior to thrombectomy in patients with large vessel occlusion stroke preserves neurological stability and reduces mortality compared to the conventional 30° elevation.

Neurology Specialties

Evaluating Intra-Arterial Tenecteplase Post-Thrombectomy in Large Vessel Occlusion Stroke: Safety and Early Efficacy from a Dose-Escalation Randomized Trial

By MedXY 09/11/2025

Adjunctive intra-arterial tenecteplase after successful reperfusion in anterior circulation large vessel occlusion stroke demonstrates an acceptable safety profile at low doses, supporting further investigation into its therapeutic potential.

Clinical Updates Neurology news Specialties Urology

Behavioral Therapy Matches Drug Efficacy for Overactive Bladder in Parkinson’s Disease: Insights from a Randomized Noninferiority Trial

By MedXY 09/11/2025

A 12-week randomized trial demonstrates that behavioral therapy is noninferior to solifenacin in treating overactive bladder symptoms in Parkinson disease, with fewer adverse effects, supporting behavioral therapy as a frontline treatment option.

Clinical Updates Neurology news

Inflammatory Exposure Amplifies Depressive Symptoms in Older Adults with Insomnia: Insights from a Randomized Clinical Trial

By MedXY 09/11/2025

A randomized clinical trial reveals older adults with insomnia have heightened depressive responses to inflammatory challenge, underscoring the need for targeted depression monitoring and prevention strategies in this vulnerable population.

Clinical Updates Neurology news OB/GYN & Women's Health Specialties

Innovations in Prenatal Care: In Utero Embolization for Vein of Galen Malformation

By MedXY 09/10/2025

In utero embolization for fetal Vein of Galen malformation shows early promise in reducing mortality and neurodevelopmental delays, despite increased risk of preterm delivery.

Family Medicine & Nutrition Neurology news Specialties

Anti-Inflammatory Diet and Alzheimer’s Disease Mortality: Insights from a National Cohort Study

By MedXY 09/07/2025

Higher adherence to an anti-inflammatory diet is linked to lower all-cause mortality and a trend toward reduced Alzheimer's disease mortality, particularly among men and non-Hispanic Whites, highlighting dietary modification as a potential strategy to mitigate neuroinflammation and AD risk.