The Effect of Chitosan Supplementation on Liver Function, Hepatic Steatosis Predictors, and Metabolic Indicators in Adults with Non-Alcoholic Fatty Liver Disease: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial

The Effect of Chitosan Supplementation on Liver Function, Hepatic Steatosis Predictors, and Metabolic Indicators in Adults with Non-Alcoholic Fatty Liver Disease: A Randomized, Double-Blinded, Placebo-Controlled Clinical Trial

This clinical trial evaluates chitosan supplementation's impact on liver health and metabolic markers in adults with NAFLD, showing potential benefits alongside a low-calorie diet.
Mediterranean Diet Combined with Early Time-Restricted Feeding: A Promising Strategy for MASLD – Insights from the CHRONO-NAFLD Trial

Mediterranean Diet Combined with Early Time-Restricted Feeding: A Promising Strategy for MASLD – Insights from the CHRONO-NAFLD Trial

A 12-week hypocaloric Mediterranean diet with early time-restricted feeding improved glycaemic control and cardiometabolic risk in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) compared to unrestricted timing or late time-restricted feeding.
Distinct Genomic Mutation Patterns in Early-Onset Colorectal Cancer: Implications for Clinical Stratification and Precision Medicine

Distinct Genomic Mutation Patterns in Early-Onset Colorectal Cancer: Implications for Clinical Stratification and Precision Medicine

A large international study reveals unique somatic mutation profiles and higher mutational burden in hypermutated early-onset colorectal cancer, highlighting the need for age-specific molecular diagnostics and management strategies.