Critical Care – Page 2

Enhancing Family Support in ICUs: Insights from the FICUS Cluster Randomized Clinical Trial

By MedXY 09/11/2025

A nurse-led, interprofessional family support intervention in ICUs modestly increased family satisfaction and significantly improved communication quality and emotional support, addressing a critical gap in family-centered critical care.

Critical Care news Specialties

Top Ten Essential Tips for Palliative Care Clinicians Consulting in Intensive Care Units

By MedXY 09/07/2025

This article provides ten practical tips for palliative care clinicians to optimize consultation effectiveness in ICUs, emphasizing collaboration, communication, cultural respect, conflict resolution, and transition planning to improve patient and family outcomes.

Clinical Updates Critical Care Emergency Medicine Gastroenterology news Specialties

Parecoxib and Imrecoxib Sequential Therapy: A Breakthrough in Managing Severe Acute Pancreatitis

By MedXY 09/05/2025

This multicentre trial shows sequential use of COX-2 inhibitors parecoxib and imrecoxib significantly reduces severe acute pancreatitis (SAP) incidence, shortens organ failure duration, lowers local complications, and decreases 30-day mortality, with a good safety profile.

Critical Care news Public Health Respiratory Specialties

Global Shifts in Pulmonary Embolism Mortality: A 2001-2023 WHO Database Analysis

By MedXY 08/25/2025

Analysis of WHO data reveals declining global pulmonary embolism mortality overall, with marked differences by region and income, highlighting urgent needs in lower-middle-income countries.

Critical Care Gastroenterology Specialties

Antibiotic Exposure as a Major Risk Factor for Clostridioides difficile Infection: Evidence from a Large Israeli Cohort and Systematic Reviews

By MedXY 08/21/2025

Recent research confirms that antibiotic exposure doubles the risk of hospital-onset Clostridioides difficile infection (CDI), especially in non-carriers, underscoring the central role of antibiotic stewardship and the need for additional preventive strategies in asymptomatic carriers.

Cardiology Critical Care news Specialties

C-Reactive Protein as a Prognostic Biomarker in Infarct-Related Cardiogenic Shock: Insights from the ECLS-SHOCK Trial

By MedXY 08/16/2025

Elevated CRP levels independently predict short-term mortality in acute myocardial infarction complicated by cardiogenic shock, with extracorporeal life support showing no survival benefit regardless of CRP levels or admission timing.

Critical Care news Specialties

Iloprost in Severe Septic Shock with Persistent Hypoperfusion: Insights from a Rigorous Randomized Trial

By MedXY 08/13/2025

A recent double-blind RCT shows iloprost did not reduce organ failure severity in septic shock patients with persistent hypoperfusion, highlighting challenges in improving outcomes despite theoretical benefits in microcirculation.

Critical Care news Specialties

Normosol-R versus Lactated Ringers in Critical Care: Evaluating Balanced Crystalloids for Optimal Patient Outcomes

By MedXY 08/13/2025

A randomized trial evaluating Normosol-R versus lactated Ringers in critically ill adults found no significant difference in acid-base balance, kidney replacement therapy rates, or 30-day mortality, supporting comparable efficacy between these balanced crystalloids.

Critical Care news Specialties

UK-ROX Trial: Conservative Oxygen Strategy in Mechanically Ventilated ICU Patients — No 90‑Day Survival Benefit

By MedXY 08/09/2025

The UK-ROX randomized trial (n=16,500) found that targeting SpO2 90% (88–92%) to reduce oxygen exposure did not reduce 90‑day all‑cause mortality versus usual care in mechanically ventilated adults.

Clinical Updates Critical Care news Specialties

Assessing the Impact of a Ketogenic Diet in Critically Ill Sepsis Patients: An Open-Label Randomized Controlled Trial

By MedXY 08/08/2025

This trial demonstrates that a ketogenic diet safely induces stable ketosis in sepsis patients, improving metabolic parameters and immune regulation without adverse effects, suggesting potential benefits for sepsis-related organ dysfunction.

Clinical Updates Critical Care news Nursing & care Pediatrics Specialties

Intensive Nurse Home Visiting and Early Childhood Outcomes: A Randomized Clinical Trial

By MedXY 08/04/2025

A randomized trial assessing the impact of Nurse-Family Partnership home visits on child health and utilization over two years found no significant reduction in adverse outcomes but some decrease in emergency department use.

Critical Care news Specialties

Memorize the “Anaphylactic Shock” Emergency Resuscitation Sequence to Easily Handle Critical Emergency Cases!

By Dr.Paul 08/03/2025

Severe allergic reaction refers to a sudden, severe, potentially life-threatening systemic allergic reaction in the…

Anesthesiology Clinical Updates Critical Care news Pediatrics Specialties

Inhaled Isoflurane: A Noninferior Alternative to Midazolam for Pediatric ICU Sedation

By MedXY 07/31/2025

A multicenter phase 3 trial finds inhaled isoflurane as effective as intravenous midazolam for sedation in mechanically ventilated children, with added benefits of reduced opioid use and faster extubation.