Mechanical Thrombectomy Superior to Anticoagulation Alone for Rapid Right Ventricular Recovery in Intermediate-High Risk Pulmonary Embolism: Results from the STORM-PE Trial
Posted inCardiology Critical Care news

Mechanical Thrombectomy Superior to Anticoagulation Alone for Rapid Right Ventricular Recovery in Intermediate-High Risk Pulmonary Embolism: Results from the STORM-PE Trial

The STORM-PE trial, the first randomized controlled trial of its kind, demonstrates that computer-assisted vacuum thrombectomy (CAVT) significantly improves right ventricular recovery and reduces clot burden compared to anticoagulation alone in patients with intermediate-high risk pulmonary embolism.
Decompressive Craniectomy Benefits Persist Across Deep Intracerebral Hemorrhage Locations: A SWITCH Trial Analysis
Posted inCritical Care Neurology news

Decompressive Craniectomy Benefits Persist Across Deep Intracerebral Hemorrhage Locations: A SWITCH Trial Analysis

A post hoc analysis of the SWITCH trial demonstrates that the clinical benefits of decompressive craniectomy in reducing death and severe disability are consistent across different anatomical locations of deep supratentorial intracerebral hemorrhage, including the basal ganglia, internal capsule, and thalamus.
Combined Multiplex PCR and Procalcitonin Strategy Fails to Increase Antibiotic-Free Days in Critically Ill Patients with CAP: Insights from the MULTI-CAP Trial
Posted inCritical Care Infectious Diseases news Respiratory

Combined Multiplex PCR and Procalcitonin Strategy Fails to Increase Antibiotic-Free Days in Critically Ill Patients with CAP: Insights from the MULTI-CAP Trial

The MULTI-CAP trial demonstrated that combining multiplex PCR and procalcitonin did not significantly increase the number of antibiotic-free days by Day 28 in ICU patients with pneumonia, although it did successfully reduce the cumulative duration of antibiotic therapy by three days without increasing adverse events.
Beyond Survival: Unpacking the Hemodynamic and Metabolic Benefits of Microaxial Flow Pumps in STEMI-Related Cardiogenic Shock
Posted inCardiology Critical Care news

Beyond Survival: Unpacking the Hemodynamic and Metabolic Benefits of Microaxial Flow Pumps in STEMI-Related Cardiogenic Shock

Recent substudies from the DanGer Shock trial demonstrate that microaxial flow pumps significantly improve hemodynamics, accelerate lactate clearance, and reduce vasopressor needs in STEMI-related cardiogenic shock, though sex-specific outcomes are heavily influenced by age and treatment delays.
Higher Hospital-Level Utilization of Continuous Kidney Replacement Therapy Associated with Reduced Mortality in Critically Ill Patients
Posted inCritical Care Nephrology news

Higher Hospital-Level Utilization of Continuous Kidney Replacement Therapy Associated with Reduced Mortality in Critically Ill Patients

A large-scale multicenter study reveals that hospitals with higher utilization rates of continuous kidney replacement therapy (CKRT) achieve significantly lower 90-day mortality for critically ill AKI patients compared to low-utilization centers, highlighting a critical volume-outcome relationship in intensive care.