Passive leg raising–induced change in pulse pressure variation (PPV) may help identify preload responsiveness during pressure support ventilation (PSV), but its value appears greatest when inspiratory effort is low, as estimated by airway occlusion pressure at 100 ms (P0.1).
In this prospective ICU study, the PPV response to PLR outperformed baseline PPV and PLR-induced pulse pressure change.
The findings suggest a potentially simpler bedside approach to fluid decision-making in selected spontaneously breathing patients, though validation in larger cohorts is still needed.
