The G-oncoCOACH trial is a multicentre randomized controlled study evaluating CGA combined with intensive patient coaching in elderly patients with solid tumors undergoing systemic therapy.
Integration of a geriatric team for implementing GA-based recommendations and providing extensive coaching resulted in a clinically meaningful 10.9-point improvement in global health status-related quality of life at 6 months versus standard oncology care.
Adherence to geriatric assessment-based recommendations was significantly higher in the intervention group, and factors such as low baseline QoL and high comorbidity predicted QoL improvement.
This study supports implementation of CGA with multidisciplinary geriatric involvement and patient coaching to improve outcomes in older oncology patients.
