OB/GYN & Women’s Health – Page 8

Phenotyping Preeclampsia Using Unsupervised Machine Learning: A Prospective Cohort Study

By MedXY 06/06/2026

Unsupervised machine learning identified three distinct preeclampsia phenotypes linked to timing of delivery, placental dysfunction, fetal growth, and complications, suggesting a path toward more personalized risk assessment and management.

news OB/GYN & Women’s Health Public Health

Severe Maternal Morbidity at Delivery Is Linked to Shorter and Less Exclusive Breastfeeding in Nulliparous U.S. Patients

By MedXY 06/05/2026

In a large prospective U.S. cohort, severe maternal morbidity did not reduce breastfeeding initiation, but it was associated with lower odds of breastfeeding beyond 6 months and of exclusive breastfeeding.

Neurology news OB/GYN & Women’s Health

Pregnancy Complications Signal Long-Term Maternal Risk of Subarachnoid Hemorrhage in a 50-Year Swedish Cohort

By MedXY 06/05/2026

In a nationwide Swedish cohort, several adverse pregnancy outcomes were linked to higher long-term maternal risk of subarachnoid hemorrhage, supporting pregnancy as an early vascular stress test.

news OB/GYN & Women’s Health Oncology

Transcriptome Profiling With CCNA2 and E2F1 May Identify Platinum Insensitivity and Refine Prognosis in Endometrial Cancer

By MedXY 06/04/2026

TCGA-based transcriptome analysis suggests high CCNA2 and E2F1 expression marks poor progression-free survival and probable platinum insensitivity in endometrial cancer, supporting pretreatment molecular stratification and alternative therapeutic selection.

Diabetes & Endocrinology news OB/GYN & Women’s Health

Long-Term Risk of Hypothyroidism After Thyroid Abnormalities Identified in Pregnancy

By MedXY 06/04/2026

Thyroid abnormalities found during pregnancy, especially when subclinical hypothyroidism and TPO antibodies coexist, can signal a much higher long-term risk of overt hypothyroidism, supporting ongoing thyroid follow-up after delivery.

news OB/GYN & Women’s Health Oncology

Fovinaciclib for First-Line Therapy of Advanced Breast Cancer: A Randomized Clinical Trial

By MedXY 06/03/2026

Adding fovinaciclib to first-line aromatase inhibitor therapy significantly prolonged progression-free survival in hormone receptor-positive, ERBB2-negative advanced breast cancer with manageable toxicity and preserved quality of life.

news OB/GYN & Women’s Health Oncology

More Than Half of Patients With Atypical Endometrial Hyperplasia Had Occult Cancer at Hysterectomy in a Minority-Enriched Urban Cohort

By MedXY 06/01/2026

A single-center retrospective study found unexpectedly high rates of concurrent endometrial carcinoma and Mayo-criteria risk features among patients with atypical endometrial hyperplasia in a predominantly racial and ethnic minority population.

Gastroenterology news OB/GYN & Women’s Health

Postmarketing Data Link Fezolinetant Primarily to Early Transaminase Elevations Rather Than Overt Liver Injury

By MedXY 06/01/2026

FAERS postmarketing data suggest fezolinetant is associated with an early hepatic adverse event reporting signal, driven mainly by liver enzyme elevations rather than consistent severe clinical liver injury.

Diabetes & Endocrinology news OB/GYN & Women’s Health

Less Than 5 kg of Gestational Weight Gain in Type 2 Diabetes Was Linked to Lower Risk of LGA, Hypertensive Disorders, NICU Admission, and Cesarean Delivery

By MedXY 05/31/2026

In a retrospective cohort of pregnancies complicated by type 2 diabetes, gestational weight gain under 5 kg was associated with lower odds of several adverse perinatal outcomes without a statistically significant rise in preterm birth or small-for-gestational-age infants.

Cardiology news OB/GYN & Women’s Health

Premature Natural Menopause Signals Higher Lifetime Coronary Heart Disease Risk in Both Black and White Women

By MedXY 05/31/2026

A pooled US cohort analysis found that natural menopause before age 40 was associated with about a 40% higher lifetime risk of coronary heart disease in both Black and White women, supporting its use as a routine cardiovascular risk-enhancing factor.

news OB/GYN & Women’s Health Oncology

Beyond Extrapolation: Immunotherapy Outcomes in Recurrent Vulvovaginal Carcinoma

By MedXY 05/29/2026

This retrospective study found that immune checkpoint inhibitors produced modest overall benefit in recurrent vulvar and vaginal carcinoma, but a small subset of patients had durable responses lasting months.

news OB/GYN & Women’s Health

Association Between Surgical Volume and Postoperative Complications After Posterior Deep Infiltrating Endometriosis Surgery: A Nationwide Study

By MedXY 05/28/2026

A nationwide French study found that hospitals performing at least 40 posterior deep infiltrating endometriosis surgeries per year had fewer severe postoperative complications, supporting referral to experienced, high-volume centers.

news OB/GYN & Women’s Health Psychiatry

Association Between Delivery Mode and Postpartum Psychiatric Conditions

By MedXY 05/28/2026

A large U.S. cohort study found higher rates of postpartum psychiatric conditions after planned or unplanned cesarean delivery, but not after successful operative vaginal delivery, highlighting the need for closer postpartum mental health follow-up.

Diabetes & Endocrinology news OB/GYN & Women’s Health

Automated Insulin Delivery Improves Glycemia During Labor and Early Postpartum in Type 1 Diabetes: Clinical Insights From the CIRCUIT Trial

By MedXY 05/28/2026

A prespecified CIRCUIT analysis found that Control-IQ closed-loop insulin delivery improved intrapartum time in range and reduced early postpartum hypoglycemia versus standard care in women with type 1 diabetes, without new safety concerns.

Nephrology news OB/GYN & Women’s Health

Proteinuria in Preeclampsia and Long-Term Risk of Maternal Kidney and Cardiovascular Disease

By MedXY 05/26/2026

Higher proteinuria in preeclampsia was linked to greater long-term risk of maternal hypertension and chronic kidney disease, with overall increased risk of cardiovascular disease as well.

news OB/GYN & Women’s Health

Does the order of ablation of vein-to-vein placental connections during fetoscopic laser photocoagulation affect outcomes in twin-twin transfusion syndrome?

By MedXY 05/26/2026

In TTTS, a post hoc analysis found that treating vein-to-vein placental connections at the end of fetoscopic laser surgery was linked to worse donor and recipient survival than earlier treatment.

Diabetes & Endocrinology news OB/GYN & Women’s Health

Prepregnancy Insulin Resistance and Fertility Outcomes in Women With PCOS

By MedXY 05/26/2026

Higher insulin resistance before pregnancy was linked to poorer ovulation, lower pregnancy and live-birth rates, and more gestational diabetes in women with PCOS. Improving insulin resistance during treatment was associated with better pregnancy outcomes.

Cardiology news OB/GYN & Women’s Health

Women with Chronic Coronary Artery Disease: Long-Term Outcomes After PCI vs CABG

By MedXY 05/26/2026

In women with chronic severe coronary artery disease, CABG was linked to lower long-term rates of death, stroke, heart attack, repeat revascularization, and cardiovascular readmission than PCI.

news OB/GYN & Women’s Health Oncology

Cost-effectiveness of Pembrolizumab for FIGO 2014 Stage III-IVA Cervical Cancer in the United States

By MedXY 05/20/2026

Pembrolizumab plus chemoradiotherapy improved survival and quality-adjusted survival for FIGO 2014 stage III-IVA cervical cancer and was projected to be cost-effective in the U.S. at a $150,000/QALY threshold.

news OB/GYN & Women’s Health Pathology & Lab Medicine/Bệnh học

Microbial and Metabolic Correlates of Endometrial Dysfunction in Polycystic Ovary Syndrome: A Translational Study

By MedXY 05/20/2026

This study links PCOS-related miscarriage risk to gut microbiome changes, especially reduced Parabacteroides merdae and higher isoleucine, which may promote endometrial senescence and impair pregnancy outcomes.