Centralized expert review of clinical and imaging data in suspected axial spondyloarthritis (axSpA) enhances diagnostic precision compared to local assessments.
Over 969 cases evaluated prospectively via a telemedicine platform demonstrated a 33.7% discrepancy when local diagnoses labeled axSpA but experts identified alternative causes.
Interpretation of imaging findings, especially of sacroiliac joints and spine, was a major driver of diagnostic differences between local and central evaluations.
Telemedicine-facilitated centralized review may reduce misdiagnosis, improving targeted treatment initiation and patient outcomes in axSpA.