Analyzing Variability in Pediatric ECPR Survival After In-Hospital Cardiac Arrest: Development and Validation of a Risk-Standardized Survival Model

A clinical prediction model for survival after pediatric extracorporeal cardiopulmonary resuscitation (ECPR) was developed and internally validated using the Extracorporeal Life Support Organization Registry data from 2020 to 2023.
The model incorporated 14 routinely available clinical variables demonstrating fair discrimination and strong calibration for survival to hospital discharge.
Using risk-standardized survival rates (RSSRs), significant inter-hospital variation in pediatric ECPR outcomes was identified, indicating institutional factors influence survival beyond patient risk profiles.
Further external validation is warranted before widespread clinical application for benchmarking pediatric ECPR centers.

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