亜臨床性甲状腺機能低下症

Levothyroxine Treatment and Cardiometabolic Biomarkers in Older Adults with Subclinical Hypothyroidism: A Comprehensive Review

By MedXY 08/15/2026

Levothyroxine treatment in older adults with subclinical hypothyroidism shows limited impact on cardiometabolic biomarkers overall but may benefit those with higher TSH levels, highlighting nuanced treatment implications and the need for tailored therapeutic strategies.

Diabetes & Endocrinology news Pathology & Lab Medicine/Bệnh học

Prevalence and Clinical Characteristics of Macro-TSH in Patients with Subclinical Hypothyroidism

By MedXY 06/07/2026

Macro-TSH was rare but clinically important in patients with subclinical hypothyroidism, sometimes mimicking true thyroid disease and leading to unnecessary levothyroxine use. Specialized testing confirmed multiple immunoglobulin-linked TSH complexes.

Diabetes & Endocrinology news OB/GYN & Women’s Health

Long-Term Risk of Hypothyroidism After Thyroid Abnormalities Identified in Pregnancy

By MedXY 06/04/2026

Thyroid abnormalities found during pregnancy, especially when subclinical hypothyroidism and TPO antibodies coexist, can signal a much higher long-term risk of overt hypothyroidism, supporting ongoing thyroid follow-up after delivery.

Cardiology Diabetes & Endocrinology news

Thyroid Dysfunction Is a Cardiovascular Risk Multiplier, but Treatment Benefits Depend on Phenotype, Severity, and Age

By MedXY 06/03/2026

Thyroid dysfunction reshapes lipid metabolism, vascular tone, cardiac performance, and rhythm. Cardiovascular risk is clearest at the extremes of thyroid status, while treatment decisions in subclinical disease should remain individualized.

Cardiology Clinical Updates Diabetes & Endocrinology news

Levothyroxine in the Ageing Patient: Re-evaluating Cardiovascular Outcomes in Subclinical Hypothyroidism through the ACEL-UK-ETT Trial

By MedXY 03/20/2026

This review analyzes the ACEL-UK-ETT emulated target trial, demonstrating that long-term levothyroxine therapy in older adults with subclinical hypothyroidism significantly reduces cardiovascular events and all-cause mortality without compromising bone health, provided age-specific TSH thresholds are utilized.

Clinical Updates Diabetes & Endocrinology news

The Interplay of Aging and Chronic Iodine Excess on Thyrotropin Dynamics: A 20-Year Longitudinal Synthesis

By MedXY 03/10/2026

This review analyzes a landmark 20-year study highlighting how chronic iodine excess and aging synergistically elevate TSH levels, revealing that iodine-induced thyroid changes persist even after dietary reduction.