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High-Dose Aflibercept 8 mg Demonstrates Sustained Visual Gains and Durability in Polypoidal Choroidal Vasculopathy
Posted innews Ophthalmology

High-Dose Aflibercept 8 mg Demonstrates Sustained Visual Gains and Durability in Polypoidal Choroidal Vasculopathy

Posted by MedXY By MedXY 12/24/2025
This post hoc analysis of the PULSAR trial reveals that aflibercept 8 mg provides noninferior visual outcomes and comparable anatomic regression to standard 2 mg dosing in PCV patients, while allowing for significantly extended treatment intervals and reduced injection burden.
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Metformin and Age-Related Macular Degeneration: Current Evidence on Development and Progression
Posted inOphthalmology Specialties

Metformin and Age-Related Macular Degeneration: Current Evidence on Development and Progression

Posted by MedXY By MedXY 10/21/2025
This review synthesizes current evidence from large cohorts, meta-analyses, and randomized trials evaluating metformin's association with AMD development and progression, highlighting a nuanced but inconclusive protective potential requiring further prospective studies.
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  • Whole-Genome Sequencing Suggests Casual Community Contact Drives Much of Drug-Resistant Tuberculosis Transmission in Durban
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