regenerative medicine

Therapeutic Potential of Autologous Blood Derivatives in Tissue Regeneration: A Systematic Review of Clinical Evidence and Mechanistic Insights

By MedXY 03/08/2026

This review synthesizes recent PubMed-indexed evidence on autologous blood-derived therapies, such as PRP and PRF, highlighting their role in accelerating wound healing through growth factor signaling and cellular recruitment.

news Pediatrics

Cellular Therapy for In-Utero Myelomeningocele Repair: Results from the CuRe Phase 1 Trial

By MedXY 03/06/2026

This phase 1 study evaluates the safety of placenta-derived mesenchymal stem cells (PMSCs) seeded on an extracellular matrix for in-utero repair of myelomeningocele, demonstrating successful surgical outcomes and no cell-related adverse events in six patients.

Neurology news Orthopedics

Restoring Movement: How Polylaminin is Revolutionizing Spinal Cord Injury Treatment

By MedXY 02/07/2026

Brazilian scientists have developed Polylaminin, a protein derived from human placenta that stimulates nerve regeneration. In early trials, six paralyzed patients regained the ability to walk, prompting official Phase I clinical trials to begin this year.

Dermatology news Plastic Surgery

Bio-Engineered Autologous Skin Grafts Outperform Gold Standard in Burn Care: 1-Year Phase IIB Results

By MedXY 12/29/2025

A Phase IIB trial demonstrates that denovoSkin™, an autologous bio-engineered skin graft, offers a significantly higher expansion ratio and superior scar outcomes compared to split-thickness skin grafts in burn patients, potentially revolutionizing the treatment of deep partial and full-thickness wounds.

news Orthopedics

Stem Cell Therapy for Avascular Necrosis of the Femoral Head: Promise or Pitfall? A Comprehensive Meta-Analysis

By MedXY 10/12/2025

This meta-analysis evaluates stem cell therapy combined with mechanical support for avascular necrosis of the femoral head, highlighting modest improvements in function and delayed disease progression compared to stem cells alone.