pediatric cardiology

Sotatercept as Add-On Therapy in Pediatric Pulmonary Hypertension: Promising Outcomes from the Pediatric Pulmonary Hypertension Network

By MedXY 10/11/2026

Retrospective multi-center data demonstrate that sotatercept improves functional status, exercise capacity, and hemodynamics in children with pulmonary hypertension, with a manageable safety profile.

Cardiology news

Sex- and Age-Specific Genetic Risk Across Dilated and Arrhythmogenic Cardiomyopathy: Insights From the SHaRe Registry

By MedXY 05/26/2026

A large registry study found that genetic cardiomyopathy risk varies by sex, age, and gene. TTN truncating variants were more common and earlier in males, while DSP and non-TTN sarcomeric variants were more common in females.

Cardiology news Pediatrics

Pediatric Hypertrophic Cardiomyopathy: The High-Risk Profile of Massive Left Ventricular Hypertrophy

By MedXY 04/24/2026

A multiregistry analysis reveals that massive LVH in pediatric HCM is linked to early diagnosis, sarcomeric mutations, and heightened risks of arrhythmias, heart failure, and mortality. Nearly 25% of patients show significant LVH regression over time.

Cardiology news Otorhinolaryngology Pediatrics

A New Standard for Pediatric Vocal Fold Immobility After Cardiac Surgery: Improving Outcomes Through Injection Laryngoplasty

By MedXY 03/13/2026

Recent research highlights a standardized multidisciplinary protocol for managing unilateral vocal fold immobility in infants after cardiothoracic surgery, showing that injection laryngoplasty significantly improves oral feeding advancement and reduces dependence on feeding tubes.

Cardiology news Pediatrics

Long-Term Reality of Single-Ventricle Reconstruction: Shunt Choice, Tricuspid Regurgitation, and the Burden of Global Morbidity

By MedXY 03/11/2026

A 16-year follow-up of the SVR trial reveals that while shunt types show similar long-term outcomes overall, pre-existing tricuspid regurgitation significantly impacts survival with RVPAS, amid a staggering 87% rate of major morbidity.

Cardiology news Pediatrics

Twice-Yearly Inclisiran Transforms LDL-C Management in Adolescents with HeFH: Insights from ORION-16

By MedXY 03/10/2026

The ORION-16 trial demonstrates that inclisiran, a twice-yearly siRNA therapy, significantly and safely reduces LDL cholesterol in adolescents with heterozygous familial hypercholesterolaemia, offering a promising solution for long-term adherence and cardiovascular risk reduction in this high-risk pediatric population.

Cardiology news Pediatrics

Minima Stent System Proves Safe and Effective for Vascular Stenosis in Infants: Results of the Multicenter Pivotal Trial

By MedXY 01/18/2026

A multicenter trial confirms the Minima Stent's efficacy in treating pulmonary artery stenosis and aortic coarctation in infants. With a 97.6% success rate and growth-accommodating design, it addresses a critical unmet need in pediatric interventional cardiology.

Cardiology Clinical Updates Pediatrics Radiology Specialties

Prognostic Value of 2D Speckle Tracking Echocardiography in Multisystem Inflammatory Syndrome in Children: Insights From the MUSIC Study

By MedXY 09/06/2025

This multicenter study highlights the utility of 2D speckle tracking echocardiography for early detection and prognostication of left ventricular dysfunction in MIS-C, informing cardiovascular risk and management.