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LC-MS/MS

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Enhanced Diagnosis of Primary Aldosteronism: Comparing LC-MS/MS and Immunoassay for Urinary Aldosterone Measurement
Posted inDiabetes & Endocrinology news Pathology & Lab Medicine/Bệnh học

Enhanced Diagnosis of Primary Aldosteronism: Comparing LC-MS/MS and Immunoassay for Urinary Aldosterone Measurement

Posted by By MedXY 08/30/2026
This study demonstrates that urinary aldosterone measurement by LC-MS/MS outperforms immunoassay in diagnosing primary aldosteronism, especially when urinary sodium is within an optimal range, offering improved sensitivity and specificity for clinical use.
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LC-MS/MS Redefines Accuracy in Congenital Adrenal Hyperplasia Newborn Screening: Reducing the False-Positive Burden
Posted inDiabetes & Endocrinology news Pediatrics

LC-MS/MS Redefines Accuracy in Congenital Adrenal Hyperplasia Newborn Screening: Reducing the False-Positive Burden

Posted by By MedXY 03/12/2026
A prospective study of over 700,000 newborns demonstrates that LC-MS/MS significantly improves the positive predictive value (PPV) of CAH screening compared to traditional RIA, identifying specific steroid ratios that offer 100% PPV and reduce unnecessary clinical follow-ups.
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