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iPSC-derived cardiomyocytes

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WNT5a Signaling Disruption Drives Cardiac Pathogenesis in LMNA-Related Emery-Dreifuss Muscular Dystrophy
Posted inCardiology news

WNT5a Signaling Disruption Drives Cardiac Pathogenesis in LMNA-Related Emery-Dreifuss Muscular Dystrophy

Posted by MedXY By MedXY 06/10/2026
Aberrant WNT5a-mediated actin filament dynamics underlie cardiac dysfunction and arrhythmias in LMNA-related Emery-Dreifuss Muscular Dystrophy, revealing novel therapeutic targets via RhoA activation and actin stabilization.
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