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Immunometabolism

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Adipocyte-Driven Immunometabolic Suppression in Pancreatic Cancer: The 12,13-DiHOME/PPARγ/TAN Axis
Posted inClinical Updates news Oncology

Adipocyte-Driven Immunometabolic Suppression in Pancreatic Cancer: The 12,13-DiHOME/PPARγ/TAN Axis

Posted by By MedXY 06/03/2026
This review explores how tumour-infiltrating adipocytes release 12,13-DiHOME to trigger neutrophil ferroptosis and CXCL2 production, ultimately subverting CD8+ T cell-mediated immunity in pancreatic ductal adenocarcinoma.
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Dietary Phytomix Dibifree Reshapes T2D Management by Modulating the Gut-Pancreas-Adipose-Immune Axis
Posted inDiabetes & Endocrinology Internal Medicine news

Dietary Phytomix Dibifree Reshapes T2D Management by Modulating the Gut-Pancreas-Adipose-Immune Axis

Posted by By MedXY 01/11/2026
A randomized trial demonstrates that Dibifree, a novel dietary phytomix, improves HbA1c and adiposity in T2D patients by enhancing GLP-1 activity and modulating immune responses.
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Unlocking the Body’s Natural ‘Fire Extinguisher’: How Vitamin B3 Enhances a Novel Anti-Inflammatory Molecule
Posted inFamily Medicine & Nutrition Medical News news Specialties

Unlocking the Body’s Natural ‘Fire Extinguisher’: How Vitamin B3 Enhances a Novel Anti-Inflammatory Molecule

Posted by By MedXY 08/31/2025
A groundbreaking discovery reveals a natural anti-inflammatory molecule in the body, homocysitaconate, whose levels can be boosted by vitamin B3 supplementation, offering new hope for managing severe inflammatory diseases.
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  • Safety and Effects of Gildeuretinol Acetate on Retinal Atrophic Lesions in Stargardt Disease: Insights from the TEASE-1 Randomized Clinical Trial
  • Compartment-Specific Nodal Recurrence in Medullary Thyroid Cancer: Evaluating the Role of Contralateral Prophylactic Central Neck Dissection
  • Protocol-Based Early Intensive Lipid Management Significantly Enhances LDL-C Target Achievement Post-Acute Coronary Syndrome: Insights from the BRIDGE Trial
  • Optimizing Monitoring in Head and Neck Squamous Cell Carcinoma: Tissue-Informed ctDNA Assay Shows High Accuracy and Feasibility
  • Evaluating Voice Disorder Risks in Peri- and Post-Menopausal Women Using Hormone Replacement Therapy: Insights from a Large TriNetX Cohort
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