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Immunometabolism

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Adipocyte-Driven Immunometabolic Suppression in Pancreatic Cancer: The 12,13-DiHOME/PPARγ/TAN Axis
Posted inClinical Updates news Oncology

Adipocyte-Driven Immunometabolic Suppression in Pancreatic Cancer: The 12,13-DiHOME/PPARγ/TAN Axis

Posted by MedXY By MedXY 06/03/2026
This review explores how tumour-infiltrating adipocytes release 12,13-DiHOME to trigger neutrophil ferroptosis and CXCL2 production, ultimately subverting CD8+ T cell-mediated immunity in pancreatic ductal adenocarcinoma.
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Dietary Phytomix Dibifree Reshapes T2D Management by Modulating the Gut-Pancreas-Adipose-Immune Axis
Posted inDiabetes & Endocrinology Internal Medicine news

Dietary Phytomix Dibifree Reshapes T2D Management by Modulating the Gut-Pancreas-Adipose-Immune Axis

Posted by MedXY By MedXY 01/11/2026
A randomized trial demonstrates that Dibifree, a novel dietary phytomix, improves HbA1c and adiposity in T2D patients by enhancing GLP-1 activity and modulating immune responses.
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Unlocking the Body’s Natural ‘Fire Extinguisher’: How Vitamin B3 Enhances a Novel Anti-Inflammatory Molecule
Posted inFamily Medicine & Nutrition Medical News news Specialties

Unlocking the Body’s Natural ‘Fire Extinguisher’: How Vitamin B3 Enhances a Novel Anti-Inflammatory Molecule

Posted by MedXY By MedXY 08/31/2025
A groundbreaking discovery reveals a natural anti-inflammatory molecule in the body, homocysitaconate, whose levels can be boosted by vitamin B3 supplementation, offering new hope for managing severe inflammatory diseases.
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  • Targeting Post-Transplant Myeloid Immune Suppression in Multiple Myeloma: Why CSF-1R Blockade May Enhance Lenalidomide Maintenance After ASCT
  • Bronchoscopy in Germany Generates More Than 550 Tons of Waste Annually, With Reusable PPE Offering the Largest Immediate Reduction
  • Quantitative CT Progression Thresholds in Idiopathic Pulmonary Fibrosis May Sharpen Annual Monitoring and Risk Stratification
  • Subclinical Peripheral Vascular Leakage in Demyelinating Disease-Associated Uveitis: What Ultra-Widefield Angiography Adds Beyond Clinical Quiescence
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