gene expression – Medxy AI

Molecular Biomarkers Predicting Canakinumab Tapering Success in Systemic Juvenile Idiopathic Arthritis

By MedXY 10/02/2026

This study identifies serum and gene expression signatures predicting successful canakinumab tapering in systemic juvenile idiopathic arthritis, offering precision medicine strategies to reduce flares.

news Pediatrics Respiratory

Early Neutrophil and Persistent Eosinophil Gene Signatures in Childhood Asthma

By MedXY 06/19/2026

A longitudinal blood gene-expression study in children found an early neutrophil-driven immune pattern at age 1, followed by a persistent eosinophilic signature from 4.5 to 10.5 years in those who later developed asthma.

Allergy & Immunology Diabetes & Endocrinology news

Immune-Cell Transcriptomics and Mendelian Randomisation Identify New Causal Genes for Type 2 Diabetes Complications

By MedXY 05/16/2026

This study used immune-cell gene expression and genetic analyses to identify causal genes and immune pathways linked to type 2 diabetes and its complications, highlighting diabetic neuropathy as a distinct cluster and prioritising ten promising drug targets.

Clinical Updates news Otorhinolaryngology

Molecular Profiling of Benign Vocal Fold Lesions: Differential Gene Expression in Polyps versus Reinke’s Edema

By MedXY 03/16/2026

This review explores the transcriptomic distinctions between vocal fold polyps and Reinke's edema, focusing on the upregulation of COL1A1, FN1, and MMP-9 in polyps as key diagnostic and mechanistic markers.

Family Medicine & Nutrition Gastroenterology news Specialties

Maintaining Hunger Sensation to Delay Aging

By MedXY 08/08/2025

Research indicates that the sensation of hunger triggered by calorie restriction can influence gene expression, helping to delay aging and extend lifespan by up to 35%.