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Digital Psychiatry

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Rule-Based Chatbots Outperform LLMs in Depressive Symptom Management: A Systematic Review and Meta-Analysis
Posted inAI news Psychiatry

Rule-Based Chatbots Outperform LLMs in Depressive Symptom Management: A Systematic Review and Meta-Analysis

Posted by By MedXY 12/23/2025
A comprehensive meta-analysis indicates that rule-based chatbots provide a modest but statistically significant reduction in depressive symptoms within a 4-8 week window, whereas evidence for the clinical efficacy of Large Language Model (LLM)-based chatbots remains insufficient due to high variability.
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