curcumin – Medxy AI

The Double-Edged Sword of Curcumin: How Excessive Turmeric Supplements Can Harm Your Liver

By MedXY 09/21/2025

While turmeric's liver-regenerating benefits are celebrated, excessive intake of its active compound, curcumin, may cause serious liver damage. Understanding safe dosages and risks is critical for health.

Clinical Updates Wellness & Lifestyle

Enhanced Therapeutic Benefits of Combined Metformin and Curcumin in Women with Polycystic Ovary Syndrome: Results from a Factorial Clinical Trial

By MedXY 09/16/2025

A 12-week randomized trial demonstrates that combining metformin and nanocurcumin significantly improves lipid metabolism, glucose regulation, hormonal balance, and body metrics in women with PCOS, surpassing effects seen with either agent alone or placebo.

Clinical Updates Wellness & Lifestyle

Clinical Therapeutic Value of Curcumin Supplementation in Cardiovascular Disease, Diabetes, Cognitive Function, Aging, and Neurodegenerative Disorders: A Synthesis of Recent Evidence

By MedXY 08/18/2025

Current evidence supports curcumin supplementation for reducing cardiovascular risk factors and preventing type 2 diabetes progression, with emerging potential in cognitive decline and aging-related degenerative diseases.

Clinical Updates Wellness & Lifestyle

Curcumin Mitigates Methotrexate-Induced Ovarian Damage: Insights into Antioxidant Protection via PARP-1 and P53 Modulation

By MedXY 08/06/2025

Curcumin pretreatment reduces methotrexate-induced ovarian damage in rats by regulating oxidative stress and apoptosis pathways, highlighting a potential strategy for fertility preservation in chemotherapy.

Clinical Updates Wellness & Lifestyle

Curcumin Shows Promise in Targeting Colorectal Cancer Stem-like Cells: Mechanistic Insights and Clinical Implications

By MedXY 08/06/2025

Curcumin, derived from turmeric, targets colorectal cancer stem-like cells, inhibits tumor growth, and promotes differentiation, offering new opportunities for cancer prevention strategies.

Clinical Updates Wellness & Lifestyle

Curcumin’s Impact on Serum Inflammatory Biomarkers in Knee Osteoarthritis: Evidence from a Systematic Review and Meta-Analysis

By MedXY 08/06/2025

A systematic review and meta-analysis found that curcumin supplementation significantly reduces serum CRP and TNF-alpha in patients with knee osteoarthritis, but not other inflammatory biomarkers.