curcumin – Medxy AI

Curcumin Mitigates Methotrexate-Induced Ovarian Damage: Insights into Antioxidant Protection via PARP-1 and P53 Modulation

By MedXY 08/06/2025

Curcumin pretreatment reduces methotrexate-induced ovarian damage in rats by regulating oxidative stress and apoptosis pathways, highlighting a potential strategy for fertility preservation in chemotherapy.

Clinical Updates Wellness & Lifestyle

Curcumin Shows Promise in Targeting Colorectal Cancer Stem-like Cells: Mechanistic Insights and Clinical Implications

By MedXY 08/06/2025

Curcumin, derived from turmeric, targets colorectal cancer stem-like cells, inhibits tumor growth, and promotes differentiation, offering new opportunities for cancer prevention strategies.

Clinical Updates Wellness & Lifestyle

Curcumin’s Impact on Serum Inflammatory Biomarkers in Knee Osteoarthritis: Evidence from a Systematic Review and Meta-Analysis

By MedXY 08/06/2025

A systematic review and meta-analysis found that curcumin supplementation significantly reduces serum CRP and TNF-alpha in patients with knee osteoarthritis, but not other inflammatory biomarkers.