Clinical Therapeutic Value of Curcumin Supplementation in Cardiovascular Disease, Diabetes, Cognitive Function, Aging, and Neurodegenerative Disorders: A Synthesis of Recent Evidence
Curcumin supplementation shows moderate- to high-quality evidence for reducing cardiovascular risk factors based on a large meta-analysis of micronutrients.
A landmark randomized controlled trial demonstrated curcumin’s efficacy in preventing progression from prediabetes to type 2 diabetes by preserving β-cell function and improving insulin resistance.
Preclinical and early clinical evidence suggest curcumin’s neuroprotective and anti-inflammatory effects may benefit cognitive function, aging processes, and neurodegenerative disorders.
Curcumin’s pleiotropic mechanisms—including antioxidant, anti-inflammatory, and metabolic modulation—underpin its translational therapeutic potential across multiple chronic diseases.
