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急性膵炎

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More is Not Always Better: The GOULASH Trial Challenges High-Energy Early Nutrition in Acute Pancreatitis
Posted inGastroenterology Internal Medicine news

More is Not Always Better: The GOULASH Trial Challenges High-Energy Early Nutrition in Acute Pancreatitis

Posted by By MedXY 03/07/2026
The multicentre GOULASH trial reveals that high-energy nutrition in the early phase of acute pancreatitis does not improve outcomes and may increase risks of organ failure and pain relapse compared to a gradual caloric increase, leading to the trial's early termination for futility.
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Can a Peripheral Opioid Antagonist Break the Cycle of Recurrent Acute Pancreatitis? Insights from the PAMORA-RAP Trial
Posted inGastroenterology Internal Medicine news

Can a Peripheral Opioid Antagonist Break the Cycle of Recurrent Acute Pancreatitis? Insights from the PAMORA-RAP Trial

Posted by By MedXY 02/02/2026
The PAMORA-RAP trial suggests that naldemedine, a peripherally acting μ-opioid receptor antagonist, may reduce the risk of recurrent acute pancreatitis by nearly 50%, offering a potential first-in-class pharmacological strategy for this high-burden condition.
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  • Adjunctive Metformin with Progestin in Fertility-Sparing Treatment of Endometrial Neoplasia: Insights from the FELICIA Trial
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