Unraveling Chronic Stress: The Role of Gut Dysbiosis and Vitamin B6 Metabolism in Stress-Related Brain Disorders Independent of Cortisol

Unraveling Chronic Stress: The Role of Gut Dysbiosis and Vitamin B6 Metabolism in Stress-Related Brain Disorders Independent of Cortisol

Recent evidence reveals gut dysbiosis-induced vitamin B6 metabolic disturbances as a novel, cortisol-independent mechanism driving chronic stress-related abnormal behaviors and inflammation, highlighting probiotic and vitamin B6 supplementation as potential therapeutic strategies.
Impact of E-cigarette Use on Cardiovascular Risk, Lung Function, and Clinical Outcomes in Smokers: Insights from a Randomised Placebo-Controlled Trial

Impact of E-cigarette Use on Cardiovascular Risk, Lung Function, and Clinical Outcomes in Smokers: Insights from a Randomised Placebo-Controlled Trial

This review synthesizes trial evidence showing that nicotine-containing e-cigarettes modestly improve lipid profiles but cause no significant changes in lung function or other cardiovascular markers compared to cigarette substitutes in smokers reducing cigarette use.