Specialties – Page 22

Soft Drink Consumption and Depression: The Gut Microbiome Connection, Especially Eggerthella

By MedXY 09/28/2025

This analysis explores how soft drink consumption correlates with major depressive disorder (MDD), revealing gut microbiome alterations—particularly in Eggerthella abundance—that may mediate this association, highlighting potential intervention targets.

news Public Health Specialties

Effective Communication of Medical Numerical Information: Guidelines for Researchers

By MedXY 09/28/2025

This article outlines recommended guidelines for researchers reporting studies on communicating health-related numbers to lay audiences, highlighting common reporting issues and proposing seven key recommendations to improve clarity and synthesis of evidence.

news Pediatrics Public Health Specialties

Navigating Childhood Insurance in the US: Insights into Medicaid, CHIP, and Uninsurance Dynamics

By MedXY 09/28/2025

A simulation study reveals that 75% of US children experience publicly subsidized insurance or uninsurance periods by age 18, highlighting the impact of state Medicaid policies on pediatric coverage gaps.

Clinical Updates Neurology news

Clinically Meaningful Changes in Cognitive and Functional Measures Early in Alzheimer’s Disease: Insights from Population-Based Cohorts

By MedXY 09/28/2025

This review synthesizes evidence on clinically meaningful within-patient changes in cognitive and functional assessments among individuals transitioning to mild cognitive impairment (MCI), highlighting implications for clinical trials and early intervention in Alzheimer's disease and related dementias (ADRD).

Ophthalmology Pediatrics Specialties

Understanding Patient Acceptance of Complement Inhibitor Therapy in Geographic Atrophy

By MedXY 09/28/2025

A UK study reveals most patients with geographic atrophy are open to intravitreal complement inhibitor injections if these treatments offer vision improvement, highlighting the vital role of functional benefits in therapy acceptance.

Clinical Updates Ophthalmology Pediatrics Specialties

Atropine vs Cyclopentolate: Optimizing Premyopia Diagnosis in Preschool Children

By MedXY 09/28/2025

This study compares atropine and cyclopentolate for cycloplegia in preschoolers, finding atropine leads to less myopic refraction and may reduce premyopia overestimation. It highlights implications for precise refractive diagnosis in young children.

AI news Oncology Radiology Specialties

Advancing Precision Medicine in Hepatocellular Carcinoma: Machine Learning Radiomic Models Surpass Clinical Biomarkers in Predicting Immunotherapy Outcomes

By MedXY 09/27/2025

Integrated radiomic-clinical machine learning models outperform traditional clinical biomarkers in predicting survival and treatment response in unresectable hepatocellular carcinoma patients undergoing atezolizumab plus bevacizumab therapy.

Cardiology Clinical Updates Nephrology

Exploring the Impact of Reduced Left Ventricular Function on Outcomes After PCI in Chronic Kidney Disease Patients

By MedXY 09/27/2025

Reduced left ventricular ejection fraction (LVEF) adversely affects survival and myocardial infarction risk in patients with chronic kidney disease undergoing percutaneous coronary intervention, despite no significant difference in overall major cardiovascular events.

Cardiology Clinical Updates General Surgery Pathology & Lab Medicine Specialties

Circulating Trimethylamine N-Oxide: A Novel Biomarker for Predicting Abdominal Aortic Aneurysm Progression and Surgical Risk

By MedXY 09/27/2025

Elevated plasma TMAO levels are associated with higher risk of abdominal aortic aneurysm development, rapid aneurysm growth, and need for surgical repair, providing a promising tool for risk stratification and personalized surveillance.

AI Cardiology Specialties

Harnessing Artificial Intelligence for Enhanced Prediction of Complete Heart Block Risk via Electrocardiography

By MedXY 09/27/2025

AIRE-CHB, a novel AI-enhanced ECG model, significantly improves prediction of incident complete heart block, outperforming traditional bifascicular block assessment and offering promising clinical utility in risk stratification and management.

Cardiology news

Long-Term Survival Outcomes After Initial Stress Testing Versus Coronary CTA in Suspected CAD: Insights from the PROMISE Trial

By MedXY 09/27/2025

The PROMISE trial's 10-year follow-up shows no difference in all-cause or cardiovascular mortality between initial functional stress testing and anatomic coronary CTA in symptomatic patients with suspected coronary artery disease.

Cardiology

Sustained Benefits of Physiology-Guided Complete Revascularization in Elderly Myocardial Infarction Patients: Insights from the FIRE Trial Three-Year Follow-Up

By MedXY 09/27/2025

The FIRE randomized clinical trial demonstrates that physiology-guided complete revascularization in patients aged 75 and older with myocardial infarction and multivessel disease maintains significant reductions in death, MI, stroke, and heart failure hospitalizations over a three-year follow-up, outperforming culprit-only treatment.

Cardiology Public Health Specialties

High-Dose vs Standard-Dose Influenza Vaccine and Cardiovascular Outcomes in Older Adults: Insights from the DANFLU-2 Randomized Clinical Trial and Related Evidence

By MedXY 09/27/2025

This review synthesizes evidence on high-dose versus standard-dose influenza vaccines for cardiovascular outcomes in older adults, focusing on the large DANFLU-2 trial and complementary studies, highlighting modest cardiovascular benefits and implications for clinical practice.

Cardiology Nephrology

Abelacimab Shows Consistent Bleeding Safety Across Kidney Function in Atrial Fibrillation: Insights from the AZALEA-TIMI 71 Trial

By MedXY 09/27/2025

This analysis of the AZALEA-TIMI 71 trial reveals that abelacimab, a novel factor XI inhibitor, significantly reduces bleeding risk versus rivaroxaban in atrial fibrillation patients, regardless of kidney function, suggesting its promise for those with chronic kidney disease.

Cardiology news Specialties

High Prevalence and Clinical Impact of Sleep Apnea in Hypertrophic Cardiomyopathy: Insights from a Prospective Cohort Study

By MedXY 09/27/2025

Sleep disordered breathing affects over half of patients with hypertrophic cardiomyopathy, correlating with worsening myocardial remodeling, diastolic dysfunction, and subclinical myocardial injury, underscoring the need for clinical trials on intervention.

Cardiology Diabetes & Endocrinology Specialties

Transthyretin Cardiac Amyloidosis in Older Black and Hispanic Patients with Heart Failure: Prevalence, Genetics, and Clinical Implications

By MedXY 09/27/2025

A prospective study reveals transthyretin cardiac amyloidosis (ATTR-CA) affects a significant proportion of older Black patients with heart failure, especially men over 75, with nearly half linked to the V142I genetic variant. Hispanic prevalence is lower but still notable.

Cardiology Clinical Updates news Radiology Specialties

Advancing Noninvasive Imaging in Assessing Hemodynamic Significance of Right Coronary Artery Anomalies

By MedXY 09/27/2025

This article reviews a prospective study evaluating noninvasive anatomical and functional imaging methods to determine hemodynamic significance in right anomalous aortic origin of a coronary artery (R-AAOCA), proposing a stepwise diagnostic approach to reduce invasive testing.

Cardiology news Radiology Specialties

Linking Retinal Microvasculature to Silent Coronary Atherosclerosis: Insights from Optical Coherence Tomography Angiography

By MedXY 09/27/2025

Reduced retinal parafoveal vascular density measured by OCTA independently correlates with subclinical coronary atherosclerosis, revealing a novel noninvasive biomarker for cardiovascular risk assessment beyond traditional factors.

news Public Health Respiratory

Evaluating the 23-Valent Pneumococcal Polysaccharide Vaccine for Cardiovascular Event Prevention: Insights from a Landmark Randomized Trial

By MedXY 09/27/2025

A large randomized clinical trial demonstrated that the 23-valent pneumococcal polysaccharide vaccine (PPV23) did not significantly reduce fatal or nonfatal acute coronary syndrome and ischemic stroke among middle-aged adults at increased cardiovascular risk over seven years of follow-up.

news Public Health Respiratory Specialties

Rare Case of Multifocal Cutaneous Tuberculosis in an Immunocompetent Patient

By MedXY 09/27/2025

We present a case of multifocal cutaneous tuberculosis in a 35-year-old immunocompetent woman, highlighting diagnostic challenges and effective management with standard anti-tubercular therapy.