Dietary Lipid Sequestration and Metabolic Rewiring in Colorectal Cancer: New Mechanistic Frontiers and Therapeutic Potential
Posted inClinical Updates Gastroenterology news Oncology

Dietary Lipid Sequestration and Metabolic Rewiring in Colorectal Cancer: New Mechanistic Frontiers and Therapeutic Potential

This review synthesizes recent evidence on how colorectal cancer tissues directly absorb extrinsic long-chain fatty acids from the intestinal lumen, particularly in right-sided tumors, and explores the critical interplay between lipid metabolism, the gut microbiome, and cancer cell proliferation.
Sentinel Lymph Node Biopsy in Head and Neck Merkel Cell Carcinoma: Why High False-Negative Rates Demand Clinical Vigilance
Posted innews Oncology Otorhinolaryngology

Sentinel Lymph Node Biopsy in Head and Neck Merkel Cell Carcinoma: Why High False-Negative Rates Demand Clinical Vigilance

A comprehensive cohort study reveals that sentinel lymph node biopsy (SLNB) in head and neck Merkel cell carcinoma has a sensitivity of only 52.6% and a high failure rate. The findings suggest that clinicians must reconsider management strategies for patients with high-risk features or failed biopsies.