Medxy AI – Page 31

ACR TI-RADS Reduced Repeat Thyroid Ultrasound but Did Not Lower Biopsy or Surgery Rates in Real-World Practice

By MedXY 05/04/2026

In a large single-center retrospective study, ACR TI-RADS implementation decreased follow-up thyroid ultrasound but did not reduce fine-needle aspiration, surgery, cancer yield, or overall costs.

Diabetes & Endocrinology news Oncology

Calcitonin Doubling Rate Sharpens Postoperative Recurrence Risk Stratification in Medullary Thyroid Carcinoma With Biochemical Persistent Disease

By MedXY 05/04/2026

In medullary thyroid carcinoma with biochemical persistent disease after surgery, an early postoperative calcitonin doubling rate of at least 0.3/year strongly identified patients at higher recurrence risk and may help tailor surveillance intensity.

General Surgery news Public Health

Laparoscopic Groin Hernia Repair Showed the Lowest Long-Term Operative Recurrence in Medicare Patients, While Robotic Use Expanded Without Clear Recurrence Benefit

By MedXY 05/04/2026

A large Medicare cohort found low 5-year operative recurrence after groin hernia repair overall, with laparoscopic repair showing the lowest adjusted risk and robotic-assisted repair offering no recurrence advantage despite rapid uptake.

news OB/GYN & Women’s Health Oncology

Real-World Antibody-Drug Conjugate Outcomes in Gynecologic Cancers Appear Consistent Across Demographic Subgroups

By MedXY 05/04/2026

In a single-center real-world cohort, survival with mirvetuximab soravtansine, trastuzumab deruxtecan, and tisotumab vedotin broadly mirrored pivotal trials, with no independent survival differences by age, race, or ethnicity after adjustment.

Neurology news OB/GYN & Women’s Health

Pregnancy Outcomes Among Individuals With Cerebral Palsy: A Population-Based Cohort Study

By MedXY 05/04/2026

Canadian research reveals individuals with cerebral palsy face significantly higher risks of severe maternal complications, preterm birth, and neonatal issues during pregnancy, highlighting the need for specialized perinatal care.

Gastroenterology Infectious Diseases news

Pairing HDV RNA With Anti-HDV Levels May Sharpen Staging and Treatment Monitoring in HBV/HDV Coinfection

By MedXY 05/04/2026

In HBsAg-positive, anti-HDV-positive patients, combined measurement of HDV RNA and anti-HDV titers distinguished inactive from active disease and tracked interferon response more effectively than either marker alone.

AI Gastroenterology news

AI Radiomics Detects Visually Occult Pancreatic Cancer on CT Nearly 16 Months Before Diagnosis and Outperforms Radiologists

By MedXY 05/04/2026

A multi-institutional AI model identified pre-diagnostic pancreatic cancer on routine CT with meaningful lead time, higher sensitivity than radiologists, longitudinal stability, and externally validated specificity in a low-prevalence setting.

Gastroenterology news Oncology

Cancer Risk in Familial Adenomatous Polyposis Remains Broad Despite Preventive Surgery: Dutch Nationwide Data Highlight Rising Gastric Cancer Burden

By MedXY 05/03/2026

A nationwide Dutch cohort confirms that patients with FAP remain at markedly elevated risk for multiple gastrointestinal and extraintestinal cancers, with gastric cancer emerging as the most frequently diagnosed malignancy since 2020.

Neurology news Pediatrics

Pediatric Ischemic Stroke in Switzerland Is Still Diagnosed Too Late for Reperfusion in Most Cases

By MedXY 05/03/2026

A 24-year Swiss registry study shows modest improvement in pediatric stroke recognition, but most children are still diagnosed beyond thrombolysis and thrombectomy windows.

Neurology news Public Health

Status Epilepticus Mortality in U.S. Adults Is Rising, With the Highest Burden in Older Adults, Men, Non-Hispanic Black Populations, and the South

By MedXY 05/03/2026

A U.S. mortality analysis from 1999 to 2020 found increasing deaths from status epilepticus after 2007, with marked disparities by age, sex, race/ethnicity, and region.

Neurology news Oncology

First-Time Seizure Is Linked to a Markedly Increased Short-Term Risk of Occult Cancer

By MedXY 05/03/2026

A nationwide Danish cohort study found that adults with a first-time seizure had substantially elevated 1-year risks of neurological and nonneurological cancers, with smaller but persistent excess risk over longer follow-up.

Neurology news Pediatrics

Combined Nicotinamide Riboside and Home-Based Exercise Improved Peak VO2 Safely in Friedreich’s Ataxia

By MedXY 05/03/2026

In a phase 2 factorial trial, 12 weeks of nicotinamide riboside plus individualized exercise improved cardiopulmonary fitness in Friedreich's ataxia, with mild-to-moderate adverse events and no signal of major safety concerns.

Diabetes & Endocrinology news Ophthalmology

Teprotumumab for Thyroid Eye Disease Carries a Measurable Long-Term Dysglycemia Risk

By MedXY 05/03/2026

A large multinational cohort study found that teprotumumab use in thyroid eye disease was associated with higher risks of prediabetes, diabetes, and antidiabetes medication initiation over 5 years.

Diabetes & Endocrinology news OB/GYN & Women’s Health

Gut Microbiome Signatures May Help Explain Why Gestational Diabetes Raises Later Type 2 Diabetes Risk in Hispanic/Latina Women

By MedXY 05/03/2026

In HCHS/SOL, prior gestational diabetes was linked to a proinflammatory gut microbiome, adverse metabolite patterns, and higher future type 2 diabetes risk, suggesting a plausible microbiome-mediated pathway after pregnancy.

Diabetes & Endocrinology news Pathology & Lab Medicine/Bệnh học

Urinary Free Cortisol Thresholds Sharpen the Differential Diagnosis of ACTH-Dependent Cushing’s Syndrome

By MedXY 05/03/2026

A Spanish multicenter validation study shows that urinary free cortisol expressed as multiples of the upper limit of normal can meaningfully stratify the likelihood of ectopic ACTH secretion versus Cushing’s disease.

Clinical Updates Diabetes & Endocrinology news

Cost-Effectiveness of Continuous Glucose Monitoring Combined with Remote Patient Monitoring in Pediatric Type 1 Diabetes

By MedXY 05/03/2026

A landmark simulation study demonstrates that adding remote patient monitoring to continuous glucose monitoring in pediatric T1D patients significantly improves QALYs and is highly cost-effective compared to standard care.

Diabetes & Endocrinology Nephrology news

Visceral Fat Predicts Diabetic Kidney Disease Differently in Men and Women, With a High-Risk Signal in Leaner Men

By MedXY 05/03/2026

In a 93,532-person prospective diabetes cohort, visceral fat area independently predicted incident diabetic kidney disease, with striking sex- and BMI-specific patterns, including a U-shaped risk curve in men and elevated risk in low-VFA men.

Cardiology Internal Medicine news

PCSK9 Inhibition Lowers LDL Cholesterol in Heterozygous Familial Hypercholesterolemia Regardless of LDL Receptor Variant Function

By MedXY 05/03/2026

In a pooled nonrandomized phase 3 analysis, monthly lerodalcibep reduced LDL-C by about 50% in heterozygous familial hypercholesterolemia, with similar efficacy across LDLR functional variant categories and broad attainment of guideline-based LDL-C goals.

Cardiology news

Development and Validation of a Clinical Polygenic Risk Report in U.S.-Based Health Systems for 8 Cardiovascular Conditions

By MedXY 05/02/2026

Researchers developed and validated integrated polygenic risk scores for eight cardiovascular conditions using data from over 245,000 individuals. These scores demonstrated strong predictive power and improved risk classification, providing a clinically implementable framework for genetic risk reporting.

Cardiology Diabetes & Endocrinology news

GLP-1 Receptor Agonists Show Lower Heart Failure Risk Versus DPP-4 Inhibitors in Type 2 Diabetes

By MedXY 05/02/2026

New research comparing diabetes medications reveals GLP-1 receptor agonists lower heart failure hospitalization risk compared to DPP-4 inhibitors, while showing similar risk to SGLT-2 inhibitors in type 2 diabetes patients.

ACR TI-RADS Reduced Repeat Thyroid Ultrasound but Did Not Lower Biopsy or Surgery Rates in Real-World Practice

Calcitonin Doubling Rate Sharpens Postoperative Recurrence Risk Stratification in Medullary Thyroid Carcinoma With Biochemical Persistent Disease

Laparoscopic Groin Hernia Repair Showed the Lowest Long-Term Operative Recurrence in Medicare Patients, While Robotic Use Expanded Without Clear Recurrence Benefit

Real-World Antibody-Drug Conjugate Outcomes in Gynecologic Cancers Appear Consistent Across Demographic Subgroups

Pregnancy Outcomes Among Individuals With Cerebral Palsy: A Population-Based Cohort Study

Pairing HDV RNA With Anti-HDV Levels May Sharpen Staging and Treatment Monitoring in HBV/HDV Coinfection

AI Radiomics Detects Visually Occult Pancreatic Cancer on CT Nearly 16 Months Before Diagnosis and Outperforms Radiologists

Cancer Risk in Familial Adenomatous Polyposis Remains Broad Despite Preventive Surgery: Dutch Nationwide Data Highlight Rising Gastric Cancer Burden

Pediatric Ischemic Stroke in Switzerland Is Still Diagnosed Too Late for Reperfusion in Most Cases

Status Epilepticus Mortality in U.S. Adults Is Rising, With the Highest Burden in Older Adults, Men, Non-Hispanic Black Populations, and the South

First-Time Seizure Is Linked to a Markedly Increased Short-Term Risk of Occult Cancer

Combined Nicotinamide Riboside and Home-Based Exercise Improved Peak VO2 Safely in Friedreich’s Ataxia

Teprotumumab for Thyroid Eye Disease Carries a Measurable Long-Term Dysglycemia Risk

Gut Microbiome Signatures May Help Explain Why Gestational Diabetes Raises Later Type 2 Diabetes Risk in Hispanic/Latina Women

Urinary Free Cortisol Thresholds Sharpen the Differential Diagnosis of ACTH-Dependent Cushing’s Syndrome

Cost-Effectiveness of Continuous Glucose Monitoring Combined with Remote Patient Monitoring in Pediatric Type 1 Diabetes

Visceral Fat Predicts Diabetic Kidney Disease Differently in Men and Women, With a High-Risk Signal in Leaner Men

PCSK9 Inhibition Lowers LDL Cholesterol in Heterozygous Familial Hypercholesterolemia Regardless of LDL Receptor Variant Function

Development and Validation of a Clinical Polygenic Risk Report in U.S.-Based Health Systems for 8 Cardiovascular Conditions

GLP-1 Receptor Agonists Show Lower Heart Failure Risk Versus DPP-4 Inhibitors in Type 2 Diabetes

Comparative 1-Year Outcomes of Semaglutide, Tirzepatide, and Sleeve Gastrectomy in Obese Adults with Type 2 Diabetes: Insights from Real-World Data

Unveiling the Phenotype of Unclassified Pulmonary Hypertension: A Hidden Spectrum of Early Heart Failure with Preserved Ejection Fraction

Biomarker, Functional Status, and Quality-of-Life Trajectories Before Modes of Death in Heart Failure: Post Hoc Analysis of the FINEARTS-HF Randomized Clinical Trial

Decoding SLC4A3 Mutations in Short QT Syndrome: Insights from hiPSC-Derived Cardiomyocytes into Ventricular Arrhythmia and Sudden Cardiac Death