Outcomes of Heart Failure With Reduced, Mildly Reduced, or Preserved Ejection Fraction: ESC HF III Registry

Overview

Heart failure remains one of the most important cardiovascular conditions in Europe and worldwide, but it is not a single disease. Patients can have heart failure with reduced ejection fraction (HFrEF), mildly reduced ejection fraction (HFmrEF), or preserved ejection fraction (HFpEF). These categories reflect how well the heart pumps blood out with each beat, and they often differ in patient profile, underlying causes, and outcomes.

The ESC Heart Failure III Registry provides a contemporary, real-world picture of how patients with heart failure are doing across Europe and affiliated countries. It includes both patients admitted with acute heart failure and patients seen in outpatient clinics for chronic heart failure. The registry helps answer a practical question: what happens to these patients in the hospital and over the following year?

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