registry study – Medxy AI

Outcomes of Heart Failure With Reduced, Mildly Reduced, or Preserved Ejection Fraction: ESC HF III Registry

By MedXY 05/19/2026

The ESC HF III Registry found substantial mortality and rehospitalization across heart failure phenotypes. Risk was highest after acute hospitalization and generally worse with reduced ejection fraction, but HFmrEF and HFpEF also carried significant one-year event rates.

news Psychiatry

Clozapine Works Beyond Schizophrenia: Nationwide Evidence for Transdiagnostic Effectiveness and Safety

By MedXY 12/01/2025

Large Finnish and Swedish registry cohorts show clozapine is associated with lower psychiatric hospitalisation across schizophrenia-spectrum, bipolar disorder and severe depression without increased overall mortality or hospitalisation.

news Orthopedics

Prior Osteotomy Lowers Implant Survival and Raises TKA Complexity — but Early Pain and Function Are Similar: Results from 189,932 Dutch Arthroplasties

By MedXY 11/02/2025

A large Dutch registry analysis shows total knee arthroplasty (TKA) after prior knee osteotomy carries a modestly higher revision risk and more frequent use of stems/augments, while short-term pain and function are comparable to primary TKA.