Optimizing Gestational Weight Gain in Type 2 Diabetes: Clinical Evidence for Restricted Targets and Perinatal Benefits

Highlights

  • Restricted gestational weight gain (GWG <5 kg) in type 2 diabetes (T2DM) is associated with a 58% reduction in large-for-gestational-age (LGA) births.
  • Weight gain below 5 kg correlates with significantly lower risks of hypertensive disorders of pregnancy (aOR 0.56) and neonatal intensive care unit (NICU) admissions.
  • Current evidence does not demonstrate a statistically significant increase in small-for-gestational-age (SGA) infants or preterm births with restricted weight gain in this specific population.
  • Integration of metabolic markers, gut microbiome health, and precise glycated hemoglobin monitoring is essential for optimizing maternal-fetal outcomes.

Background

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