Confirmed disability improvement (CDI) and confirmed disability worsening (CDW) independent of attacks occur in both AQP4-IgG+ NMOSD and MOGAD patients, albeit infrequently.
Lower prior attack number correlates with higher CDI rates in AQP4-IgG+ NMOSD, underscoring the importance of early attack prevention.
Younger patient age is associated with increased chances of disability improvement in both diseases.
Annualized CDI and CDW rates are comparable between AQP4-IgG+ NMOSD and MOGAD.