CT Small-Artery Loss Tracks Severe Pulmonary Hypertension in COPD and Fibrosing ILD More Closely Than Parenchymal Damage

Highlights

In chronic lung disease, a lower CT-derived BV5art/TAV ratio, representing reduced small-artery volume relative to total arterial volume, was associated with hemodynamically confirmed severe pulmonary hypertension.

This signal was strongest in COPD, where severe pulmonary hypertension also coincided with larger central vessel volumes, supporting a pattern of intrapulmonary vascular volume redistribution.

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